Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University ...
Jun 30, 2022
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Northwestern Medicine scientists have identified an enzyme which aids tumors in evading the immune system, findings that could provide future directions for tumor treatment, according to a study published in Nature Communications.
Apr 12, 2023
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When it comes to genes associated with cancer, none have been studied more extensively than p53, a tumor suppressor gene that serves as the guardian of our genetic information. More than half of all cancers have mutations ...
Jan 15, 2016
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A new treatment regimen for patients with metastatic colon cancer appears to offer clinical benefit even when used after multiple other treatments have failed, say research physicians at Georgetown Lombardi Comprehensive ...
May 18, 2011
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When tissues are deprived of blood, as happens during a stroke or heart attack, the lack of oxygen can cause serious damage. After blood flow is restored, further damage occurs as the tissues become inflamed. This process, ...
Oct 28, 2014
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(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.
(Medical Xpress) -- Scientists at the University of Sussex have uncovered the mechanism of a key process in DNA repair that helps prevent neurodegenerative diseases such as ataxia.
Mar 14, 2012
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Scientists believe they have identified a role for PTEN, a known tumor suppressor, in removing DNA damage derived from UVB radiation, a known risk factor for non-melanoma skin cancer, according to a study published in Cancer ...
Jul 26, 2011
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Two drugs that mimic a common plant hormone effectively cause DNA damage and turn off a major DNA repair mechanism, suggesting their potential use as an anti-cancer therapy, say investigators at Georgetown University Medical ...
Feb 16, 2016
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An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived at conclusions that ...
May 3, 2023
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