DNA damage increases the risk of cancer, and researchers have found that a protein, known to rally when cells get stressed, plays a critical, early step in its repair.
Aug 3, 2015
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A new drug that blocks cancer's escape route from chemotherapy could be used to treat deadly lung and pancreatic cancers, research has revealed.
Jul 23, 2015
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Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, ...
Oct 16, 2020
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The genome of a cell is under constant attack, suffering DNA damage that requires an army of repair mechanisms to keep the cell healthy and alive. Understanding the behavior of the enzymes defending these assaults helps determine ...
Mar 17, 2015
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A team of scientists in Japan has found that a DNA modification called 5hmC – thought to be involved in turning genes on and off – localizes at sites of DNA damage and repair. They also found that a family of recently ...
Feb 11, 2016
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We take it for granted that our chromosomes won't stick together, yet this kind of cellular disaster would happen constantly were it not for a protein called TRF2. Now, scientists at The Scripps Research Institute (TSRI) ...
Feb 6, 2013
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Scientists at the University of Bristol have discovered that a mechanism for preventing mutation within important genes involves long distance scanning of DNA by a molecular motor protein.
Feb 19, 2014
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A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published ...
Feb 23, 2022
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University of Pittsburgh Cancer Institute (UPCI) researchers have identified over 125 genetic components in a chemotherapy-resistant, brain tumor-derived cell line, which could offer new hope for drug treatment to destroy ...
Dec 14, 2012
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In every cell in your body, DNA is constantly getting damaged.
Sep 21, 2015
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