Health
Study reveals tobacco's toll on women's placentas
Smoking while pregnant causes severe DNA damage to cells in the placenta and significantly impairs its function, new University of Otago research suggests.
Dec 4, 2013
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Page 39 - News tagged with damage dna
Oncology & Cancer
Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds
Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical ...
Jul 3, 2024
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Health
Antioxidants can protect against omega 6 damage—or promote it
Given omega 6 fatty acid's reputation for promoting cancer—at least in animal studies—researchers are examining the role that antioxidants play in blocking the harmful effects of this culprit, found in many cooking oils. ...
Apr 4, 2014
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Oncology & Cancer
New study discovers cancer-relevant protein shield
Researchers from the Novo Nordisk Foundation Center for Protein Research have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment. The ...
Apr 16, 2018
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Oncology & Cancer
A discovery could prevent the development of brain tumours in children
Scientists at the IRCM discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Frédéric Charron, PhD, found that a protein known as Sonic ...
Oct 2, 2014
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Medical research
Treating radiation wounds with aspirin hydrogels
Radiation is a powerful tool for treating cancer, but prolonged exposure can damage the skin. Radiation-induced skin injuries are painful and increase a person's chances of infection and long-term inflammation. Now, researchers ...
Aug 12, 2024
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Medical research
Adenovirus dampens host DNA damage response—implications for control and cancer therapy
Adenoviruses (Ad) are everywhere, and while they pose limited threat in individuals with healthy immune systems, they cause significant disease burden in immunocompromised patients. A study published on February 11th in PLOS ...
Feb 11, 2016
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Medications
ATR inhibition using gartisertib in patient-derived glioblastoma cell lines
A new research paper titled "ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines" has been published in Oncotarget.
Jan 17, 2024
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Oncology & Cancer
Scientists find potential new clues for identifying breast cancer risk
New research provides critical insights into how normal breast precursor cells may be genetically vulnerable to develop into cancer. The research is published June 4th in the inaugural issue of Stem Cell Reports, an open-access ...
Jun 4, 2013
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Oncology & Cancer
Therapies targeting DNA damage response show promising antitumor activity
Results from early-stage clinical trials show two drugs that target the DNA damage response (DDR) pathway in cancers—ATR inhibitor elimusertib and PARP inhibitor AZD5305—are safe and clinically beneficial in treating ...
Apr 11, 2022
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