Genetics
Researcher develops safer gene therapy
A Washington State University researcher has developed a way to reduce the development of cancer cells that are an infrequent but dangerous byproduct of gene therapy.
Nov 4, 2016
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Page 9 - News tagged with defective cells
Oncology & Cancer
Scientists identify key defect in brain tumor cells
In a new study, Yale researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA. They found that the defect is highly sensitive to an existing FDA-approved drug used to treat ...
Feb 1, 2017
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Diseases, Conditions, Syndromes
Researchers identify gene that controls birth defect common in diabetes
Researchers have identified a gene that plays a key role in the formation of neural tube defects, a problem commonly found in infants of pregnant women with diabetes. This is the first time the gene has been shown to play ...
May 5, 2017
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Medical research
Relationship between genes that make cells deaf to messages from good gut bacteria and OMVs identified
(Medical Xpress)—A team of researchers from several instantiations in the U.S. has found a connection between two defective genes in humans and the messages that are sent from a type of good bacteria and Irritable Bowel ...
Medical research
Mitochondria control stem cell fate
What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich (TUM) addressed this question by generating a new ...
Oct 27, 2016
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Diseases, Conditions, Syndromes
Weed-killer compounds also kill parasite sometimes found in cat feces
The parasite Toxoplasma gondii infects up to one-third of the human population, experts say. Sometimes transmitted to humans from infected cat feces or litter, the protozoan can cause severe and even deadly illnesses in immunocompromised ...
Apr 1, 2022
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Medical research
Scientists find potential target for treating mitochondrial disorders
Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety ...
Mar 27, 2014
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Genetics
3D genome architecture influences SCID-X1 gene therapy success
Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...
Oct 6, 2023
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Oncology & Cancer
Leukemia treatment breakthrough for babies
Babies with leukemia could get an array of new treatments after scientists used genetic engineering to reproduce a gene defect found in the disease.
Oct 7, 2022
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Genetics
New insights into little known but common birth defect: Congenital diaphragmatic hernia
Congenital diaphragmatic hernia (CDH) is not as well known as muscular dystrophy and cystic fibrosis, but like them it is a life-threatening birth defect, and is just as common. Occurring in one in 3,000 births, CDH causes ...
Mar 25, 2015
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