An experimental model uses genetics-guided biomechanics and patient-derived stem cells to predict what type of inherited heart defect a child will develop, according to authors of a new study in the journal Cell.
May 19, 2016
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Each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases recessive occur only when both the father and the mother are healthy carriers of the same defective gene which can ...
Mar 17, 2016
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The aorta, the body's largest artery, is like a hose through which our blood flows. When the hose is squeezed, the pump (i.e., the heart) is forced to work harder. In a new study, Yale researchers investigated factors that ...
Feb 9, 2016
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All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can migrate to other ...
Jan 25, 2016
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The oral drug ivacaftor appears to be safe and could be beneficial to young children between the ages of 2 and 5 with a specific type of cystic fibrosis, according to new research published in The Lancet Respiratory Medicine ...
Jan 21, 2016
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(HealthDay)—What if faulty genes in your DNA could be easily corrected, avoiding the ravages of diseases like cystic fibrosis or certain cancers?
Dec 3, 2015
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Balanced chromosomal abnormalities (BCAs), a category of structural changes to the human genome, may account for a large portion of birth defects related to brain development and function, according to research presented ...
Oct 11, 2015
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Researchers at the University of Oslo and Oslo University Hospital have found the genetic cause of a previously undescribed disease. With this, they have solved an over ten year old medical conundrum.
Sep 1, 2015
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To mend a broken heart—that is, to regenerate a damaged cardiac muscle—it helps to know how hearts are built. "How does one stem cell, which has no specific identity, develop into multiple cell types that organize into ...
Aug 4, 2015
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Fatih Uckun, Jianjun Cheng and their colleagues have taken the first steps towards developing a so-called "smart bomb" to attack the most common and deadly form of childhood cancer—called B-lineage acute lymphoblastic leukemia ...
Nov 5, 2014
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