Immune checkpoint inhibitors, which unleash the immune response against tumor cells, have revolutionized cancer treatment; however, the medications aren't effective in a large number of patients, including those with colorectal ...
Oct 11, 2021
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The immune system is highly complex. For example, a particular class of cells called mononuclear phagocytes (MNPs) plays important roles in the uptake and disposal of damaged cells, the elimination of invasive pathogens and ...
Sep 14, 2021
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CD8+ T cells—known as "killer" T cells—are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.
Sep 10, 2021
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For most, the relentless snapping of camera shutters is an all-too-familiar sound associated with trips and vacations. When venturing to a new place, travelers everywhere are constantly on the search for that picture-perfect, ...
Sep 6, 2021
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The body's immune system can recognize and attack cancer cells, but when those are able to overcome this assault, malignant tumors develop in patients. New research led by investigators at Massachusetts General Hospital (MGH) ...
Aug 11, 2021
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The psychedelic drug psilocybin, a naturally occurring compound found in some mushrooms, has been studied as a potential treatment for depression for years. But exactly how it works in the brain and how long beneficial results ...
Jul 5, 2021
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Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor ...
Jun 22, 2021
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Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target ...
Jun 2, 2021
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A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as ...
May 20, 2021
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In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...
May 18, 2021
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