Neuroscience

Imaging single spine structural plasticity at the nanoscale level

For most, the relentless snapping of camera shutters is an all-too-familiar sound associated with trips and vacations. When venturing to a new place, travelers everywhere are constantly on the search for that picture-perfect, ...

Immunology

How immune cells survive their battle with cancer

The body's immune system can recognize and attack cancer cells, but when those are able to overcome this assault, malignant tumors develop in patients. New research led by investigators at Massachusetts General Hospital (MGH) ...

Psychology & Psychiatry

Psychedelic spurs growth of neural connections lost in depression

The psychedelic drug psilocybin, a naturally occurring compound found in some mushrooms, has been studied as a potential treatment for depression for years. But exactly how it works in the brain and how long beneficial results ...

Diseases, Conditions, Syndromes

A promising two-punch therapy for Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a rare cancer involving dendritic cells, a type of white blood cell that usually helps defend against infections. The current standard of care for LCH, chemotherapy, cures fewer than ...

Immunology

Stopping the onset and progression of intractable immune diseases

The development of therapeutic drugs for inflammatory bowel disease, an intractable immune disease, and multiple sclerosis—an autoimmune disorder—is gaining traction. A research team from the Department of Life Sciences ...

Medical research

Common tumor inhibitor drug triggers unfavorable immune effects

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor ...

Oncology & Cancer

Protein disguise could be new target for cancer immunotherapy

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target ...

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