Diseases, Conditions, Syndromes

In Baltimore, lower income neighborhoods have bigger mosquitoes

Low-income urban neighborhoods not only have more mosquitoes, but they are larger-bodied, indicating that they could be more efficient at transmitting diseases. So reports a Cary Institute of Ecosystem Studies-led study, ...

Diseases, Conditions, Syndromes

Anemia may contribute to the spread of dengue fever

Mosquitoes are more likely to acquire the dengue virus when they feed on blood with low levels of iron, researchers report in the 16 September issue of Nature Microbiology. Supplementing people's diets with iron in places ...

Medical research

Possible treatment on the horizon for severe dengue disease

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. ...

Diseases, Conditions, Syndromes

Dengue fever outbreak hits Latin America and Caribbean region

The Pan American Health Organization is warning against a deadly spike in dengue fever in Latin America and the Caribbean, and is calling on communities to eliminate mosquito breeding sites to combat the virus.

Diseases, Conditions, Syndromes

Philippines 'open' to dengue vaccine as outbreak kills hundreds

As hundreds die in a severe dengue outbreak in the Philippines, many of them children, President Rodrigo Duterte said Thursday he was open to lifting his government's blanket ban on the Dengvaxia vaccine.

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Dengue fever

Dengue fever (pronounced UK: /ˈdɛŋɡeɪ/, US: /ˈdɛŋɡiː/) and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. It is also known as breakbone fever. The geographical spread includes northern Australia, northern Argentina, and the entire Singapore, Malaysia, Taiwan, Thailand, Vietnam, Indonesia, Honduras, Costa Rica, Philippines, Pakistan, India, Sri Lanka, Bangladesh, Mexico, Suriname, Dominican Republic, Puerto Rico, Jamaica, Bolivia, Brazil, Guyana, Venezuela, Barbados, Trinidad and Samoa. Unlike malaria, dengue is just as prevalent in the urban districts of its range as in rural areas. Each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. Dengue is transmitted to humans by the Aedes aegypti or more rarely the Aedes albopictus mosquito, which feed during the day.

The WHO says some 2.5 billion people, two fifths of the world's population, are now at risk from dengue and estimates that there may be 50 million cases of dengue infection worldwide every year. The disease is now epidemic in more than 100 countries.

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