Diseases, Conditions, Syndromes

Candidate dengue vaccine shows promise in early-stage trial

A candidate dengue vaccine developed by scientists at the National Institutes of Health (NIH) has been found to be safe and to stimulate a strong immune response in most vaccine recipients, according to results from an early-stage ...

Diseases, Conditions, Syndromes

TIM and TAM: 2 paths used by the Dengue virus to penetrate cells

By demonstrating that it is possible to inhibit the viral infection in vitro by blocking the bonding between the virus and these receptors, the researchers have opened the way to a new antiviral strategy. These works were ...

Medications

Progress reported with candidate dengue vaccine

Trials in Thailand with a candidate vaccine for dengue, a potentially fatal mosquito-borne disease, have shown it to protect against three of the four virus strains, its French maker said Wednesday.

Diseases, Conditions, Syndromes

Rio declares dengue epidemic

Rio de Janeiro has declared a dengue epidemic after diagnosing more than 50,000 cases of the tropical mosquito-borne infection this year and over 500 in the last week alone.

Diseases, Conditions, Syndromes

Study details how dengue infection hits harder the second time around

One of the most vexing challenges in the battle against dengue virus, a mosquito-borne virus responsible for 50-100 million infections every year, is that getting infected once can put people at greater risk for a more severe ...

Diseases, Conditions, Syndromes

New discovery on how the body fights dengue fever

Worldwide, dengue fever strikes roughly 50 million people every year and takes the lives of thousands, but specific therapies or a vaccine for this mosquito-borne illness remain unavailable. A report coming out in the online ...

Diseases, Conditions, Syndromes

Small molecule hobbles dengue in vitro and in vivo

A novel compound inhibits dengue virus, as well as other closely related important human pathogens. The research is published in the September 2011 issue of the journal Antimicrobial Agents and Chemotherapy.

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