The mutations were familiar, but the patients' conditions seemed baffling at first. A team lead by Rockefeller University researchers had linked variations in an immune gene to rare bacterial infections. Shortly afterward, ...
Oct 13, 2014
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Repetitive head injuries that occur during contact sports and military service may accelerate the aging process by increasing the build-up of beta-amyloid in the brain, leading to worse disease and an increased likelihood ...
May 12, 2015
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The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is ...
Feb 17, 2015
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An interdisciplinary collaboration 10 years in the making used a materials science approach to "fingerprint" the calcium mineral deposits known as microcalcifications that reveal pathological clues to the progression of breast ...
Feb 22, 2023
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A potential new approach to treat systemic amyloidosis, invented at UCL and being developed by GlaxoSmithKline (GSK), marks the start of a successful and innovative academic-industry collaboration.
Jul 16, 2015
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A group of villagers on the Pacific island of Guam has offered some key insight into the role that an environmental toxin may play in brain changes that are a hallmark of Alzheimer's disease. And scientists studying that ...
Jan 20, 2016
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The human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer's disease, according to a new study led by researchers at the University ...
Sep 14, 2014
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Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies. This is the conclusion of a study led by researchers at Linköping University in Sweden. ...
Apr 16, 2018
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High levels of "good" cholesterol and low levels of "bad" cholesterol are correlated with lower levels of the amyloid plaque deposition in the brain that is a hallmark of Alzheimer's disease, in a pattern that mirrors the ...
Dec 30, 2013
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Two people have now died from brain hemorrhages that may be linked to an experimental Alzheimer's drug, calling into question the medication's safety.
Nov 29, 2022
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