Few cancer treatments are generating more excitement these days than immunotherapy—drugs based on the principle that the immune system can be harnessed to detect and kill cancer cells, much in the same way that it goes ...
Jan 12, 2018
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A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development. The discovery ...
Nov 23, 2017
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Researchers from The Wistar Institute discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an immunotherapeutic strategy that inhibits ...
Nov 13, 2017
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Researchers of the Chromatin and Disease Group from the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona have identified a distinctive epigenetic event in immune cells that differentiate in the tumoral microenvironment ...
Oct 3, 2017
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It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability ...
Jul 12, 2017
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Advanced prostate cancer resistant to castration therapy appears to respond well to a combination of immune checkpoint blockades and treatments that target certain immune-busting cells commonly associated with poor patient ...
Mar 9, 2017
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Some cells excite the immune system. Others soothe it. Myeloid-derived suppressor cells (MDSCs) are one type of soothing cell, and previous work shows that cancer may specifically boost production of MDSCs as a way to tamp ...
Feb 2, 2017
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Myeloid derived suppressor cells (MDSCs), produced in the bone marrow as part of the human immune response to a tumor, may have a potent immunoregulatory role following viral infection. The similarities and differences between ...
Jan 26, 2017
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Pregnant women increase their chances of vitamin B12 deficiency if they don't consume enough meat, milk or eggs. This vitamin is found only in animal products. A deficiency of the vitamin during pregnancy could have dramatic ...
Jan 24, 2017
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Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment. In the past, data have shown that trametinib, an FDA-approved ...
Nov 1, 2016
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