Researchers have reverse-engineered the outlines of a disrupted prenatal gene network in schizophrenia, by tracing spontaneous mutations to where and when they likely cause damage in the brain. Some people with the brain ...
Aug 1, 2013
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An organelle called the endoplasmic reticulum (ER) helps to process newly synthesized proteins destined for delivery to the cell membrane. When the ER becomes overloaded and begins to accumulate poorly folded proteins, an ...
Jul 31, 2013
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A mutation in a gene crucial to normal heart development could play a role in some types of congenital heart disease—the most common birth defect in the U.S. The finding, from a team in The Research Institute at Nationwide ...
Jul 29, 2013
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(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to ...
Jul 16, 2013
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Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically ...
Jul 15, 2013
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(Medical Xpress)—A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process that is activated across a vast ...
Jul 12, 2013
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St. Jude Children's Research Hospital scientists have discovered that a protein used by cancer cells to evade death also plays a vital role in heart health. This dual role complicates efforts to develop cancer drugs that ...
Jul 10, 2013
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(Medical Xpress)—Researchers have pinpointed the role of a gene known as Arl13b in guiding the formation and proper placement of neurons in the early stages of brain development. Mutations in the gene could help explain ...
Jul 2, 2013
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A new study by Valerie Hu, Ph.D., professor of biochemistry and molecular medicine at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), reports that RORA, a novel candidate gene for autism ...
Jul 1, 2013
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Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, ...
Jun 24, 2013
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