COVID-19 therapies are better in combination than alone

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité-Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms ...


Dexamethasone enhances transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors. A new study, which showed ...

Diseases, Conditions, Syndromes

Higher dose of steroid does not improve outcomes in severe COVID-19

(HealthDay)—The number of days alive without life support at day 28 did not differ among adults with COVID-19 and severe hypoxemia receiving dexamethasone 12 mg/day versus dexamethasone 6 mg/day administered intravenously ...

Oncology & Cancer

Anti-nausea drug may help some cancer patients survive longer

Patients with breast, pancreatic and certain other types of cancer may survive longer if given an anti-nausea drug during surgery, according to a large study being presented at the ANESTHESIOLOGY 2021 annual meeting. Three ...

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Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant. It is 20 to 30 times more potent than the naturally occurring hormone cortisol and 4 to 5 times more potent than prednisone.

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