Surgery

Dexamethasone treatment safe in surgery

A large scale trial by Monash University has definitively found a drug commonly used during anaesthesia before surgery to prevent nausea and vomiting does not increase the risk of a surgical wound infection as once feared.

Medications

Triplet therapy slows refractory multiple myeloma

(HealthDay)—A once-weekly regimen of selinexor, bortezomib, and dexamethasone slows the progression of relapsed or refractory multiple myeloma, according to a study published in the Nov. 14 issue of The Lancet.

Medications

COVID-19: Dexamethasone discovery carries treatment implications

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness. ...

Diseases, Conditions, Syndromes

Steroids other than dexamethasone may also help battle COVID-19

(HealthDay)—The steroid medication dexamethasone has been proven to help people severely ill with COVID-19. Now a new study hints that other drugs in the same class may also work—in the right patients.

Diseases, Conditions, Syndromes

Dexamethasone trial results confirm COVID-19 benefits but also risks

The keenly-awaited full results from a UK trial of the steroid dexamethasone were published Friday, confirming its life-saving benefits for COVID-19 patients on ventilators but suggesting it may cause harm if given too early.

Diseases, Conditions, Syndromes

WHO urges dexamethasone boom for worst virus cases

The World Health Organization called on Monday for a rapid increase in production of dexamethasone, a cheap steroid which has been shown to reduce deaths in critically ill coronavirus patients.

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Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant. It is 20 to 30 times more potent than the naturally occurring hormone cortisol and 4 to 5 times more potent than prednisone.

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