Diseases, Conditions, Syndromes

Mechanisms of kidney protection by gliflozins

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli. The discovery of kidney benefits ...

Cardiology

Increased use of newer meds for diabetic nephropathy in the U.S.

(HealthDay)—From 2010 to 2014 there was an increase in use of diabetes medications, including sulfonylureas and dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors), among patients with diabetic nephropathy, according to ...

Diseases, Conditions, Syndromes

New strategy may help prevent kidney failure in patients with diabetes

A new strategy may help halt the progression of kidney disease in patients with diabetes. The approach, which is highlighted in an upcoming issue of the Journal of the American Society of Nephrology (JASN), addresses a common ...

Diseases, Conditions, Syndromes

Autoimmune drug may help prevent kidney disease caused by diabetes

A drug currently used to treat autoimmune disease may also help prevent the kidney-damaging effects of diabetes, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). ...

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