Cardiology

Study identifies a developmental cause of cardiac hypertrophy

Investigators at Beth Israel Deaconess Medical Center (BIDMC) have identified a developmental cause of adult-onset cardiac hypertrophy, a dangerous thickening of the heart muscle that can lead to heart failure and death. ...

Medical research

Researchers create human airway stem cells from patients' cells

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as ...

Neuroscience

A new mutation behind synucleinopathies

Parkinson's disease and Lewy body dementia belong to a family of neurodegenerative disorders called synucleinopathies because they are caused by the pathological accumulation of protein alpha-synuclein into structures called ...

Diseases, Conditions, Syndromes

Inflammation drives Crohn's disease, says study

Inflammation -- not genetic susceptibility -- drives the growth of intestinal bacteria and invasive E. coli linked to Crohn's disease (CD), reports a new Cornell study.

Genetics

Scientists find molecular key to body making healthy T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation ...

Genetics

New platform poised to be next generation of genetic medicines

A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation ...

Genetics

DNA changes accelerate body's aging process

DNA changes throughout a person's life can significantly increase their susceptibility to heart conditions and other age-related diseases, research suggests.

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