Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute ...
Sep 9, 2022
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Neurons often get most of the credit for keeping our brains sharp and functioning—as well as most of the blame when it comes to brain diseases. But star-shaped cells called astrocytes, another abundant cell in the human ...
Aug 30, 2022
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125
The structure of chromatin—the mixture of DNA and proteins that form chromosomes—can affect gene expression, and certain chromatin "readers" are important for monitoring this structure often in response to environmental ...
Aug 22, 2022
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60
A rare genetic mutation could help explain why some families are more susceptible to diabetes and kidney failure, according to a new study led by University of Utah Health scientists. They say the discovery, made within multiple ...
Aug 16, 2022
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55
Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases. A first-of-its-kind study from Boston Children's Hospital now shows that the cells that ...
Aug 12, 2022
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136
An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.
Aug 9, 2022
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85
A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes. Scant and conflicting ...
Aug 1, 2022
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1011
Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance, developed ...
Jul 29, 2022
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49
Sickle cell disease is an extremely debilitating condition that affects up to 40% of the population in African countries, with patients suffering episodes of excruciating pain, organ damage and reduced life expectancy. This ...
Jul 6, 2022
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64
Three decades ago, UC Santa Barbara neuroscientist Kenneth S. Kosik first started studying a Colombian family afflicted with a genetic form of early-onset Alzheimer's disease. He and fellow researchers realized that they ...
Jun 14, 2022
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