Research on mutation 'hotspots' in DNA could lead to new insights on cancer risks
New research from Indiana University has identified "hotspots" in DNA where the risk for genetic mutations is significantly elevated.
Jul 30, 2018
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New research from Indiana University has identified "hotspots" in DNA where the risk for genetic mutations is significantly elevated.
Jul 30, 2018
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Researchers at the European Bioinformatics Institute (EMBL-EBI), the University of Dundee and the Wellcome Sanger Institute have used human and worm data to explore the mutational causes of cancer. Their study, published ...
May 1, 2018
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Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.
Jan 5, 2018
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A study published by IRB Barcelona in Nature Genetics demonstrates that the error (mutation) surveillance and repair system shows greater efficiency in the protein-coding regions of genes.
Nov 7, 2017
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Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers involved are the ...
Jul 26, 2017
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Earlier this week, for the first time, a drug was FDA-approved for cancer based on disease genetics rather than type.
May 26, 2017
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Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive ...
May 17, 2017
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DNA is replicated to pass genetic information to the daughter cells during cell proliferation. Replication errors, if not repaired, can lead to genetic mutations. For an individual organism, some DNA mutations may cause disease, ...
Aug 29, 2016
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Up to 15 percent of colorectal cancers show a genetic mutation known as DNA mismatch repair deficiency, or dMMR. Until now, little has been known about how the mutation behaves in rectal cancer patients, what causes dMMR, ...
Jul 19, 2016
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Scientists from the Institute for Basic Science (IBS) have successfully inhibited the growth of colon tumors in mice with mismatch repair deficiency. The research team, headed by the Center's director MYUNG Kyungjae, made ...
Jun 15, 2016
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