Genetics
Genetic variation contributes to pulmonary fibrosis risk
A newly published study of patients with pulmonary fibrosis has discovered multiple genetic variations that should help with future efforts to treat the disease.
Apr 15, 2013
0
0
Page 34 - News tagged with dna repair
Oncology & Cancer
Excess estrogen in pregnancy can silence BRCA1 in daughters, increasing breast cancer risk
Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 ...
Apr 9, 2013
0
0
Oncology & Cancer
Some patients with incurable tumors and BRCA mutations respond to new two-drug combination
A novel combination of two drugs has shown anti-cancer activity in patients who had incurable solid tumors and carried a germline mutation in their BRCA genes, Dana-Farber Cancer Institute researchers are reporting at the ...
Apr 7, 2013
0
0
Oncology & Cancer
Multi-tasking imatinib boosts radiotherapy for bladder tumours
Cancer drug imatinib (Glivec) could boost radiotherapy treatment to destroy bladder cancer that has spread to the bladder wall, reveals research published in Cancer Research.
Mar 4, 2013
0
0
Oncology & Cancer
Researchers identify variations in four genes associated with an increased risk of colorectal cancer
An international research team co-led by cancer prevention researcher Ulrike "Riki" Peters, Ph.D., M.P.H., and biostatistician Hsu Li, Ph.D., at Fred Hutchinson Cancer Research Center has identified variations in four genes ...
Feb 20, 2013
0
0
Medical research
How chromosomes keep their loose ends loose
We take it for granted that our chromosomes won't stick together, yet this kind of cellular disaster would happen constantly were it not for a protein called TRF2. Now, scientists at The Scripps Research Institute (TSRI) ...
Feb 6, 2013
0
0
Oncology & Cancer
DNA-repairing protein may be key to preventing recurrence of some cancers
Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein present in several ...
Jan 28, 2013
0
0
Genetics
A scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. Researchers from ...
Jan 24, 2013
0
0
Oncology & Cancer
Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...
Jan 16, 2013
0
0
Oncology & Cancer
Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Jan 3, 2013
0
0
