Medical research

Why too much DNA repair can injure tissue

DNA-repair enzymes help cells survive damage to their genomes, which arises as a normal byproduct of cell activity and can also be caused by environmental toxins. However, in certain situations, DNA repair can become harmful ...

Immunology

Sensing infection, suppressing regeneration

In a new peer-reviewed publication, University of Illinois at Chicago researchers describe how the body's response to inflammation, which helps to fight many kinds of infections, also can counterproductively suppress much-needed ...

Oncology & Cancer

Key cancer-fighting gene's secret weapons revealed

The findings revealed that a special group of genes that function within the body's normal DNA repair process were vital to the effectiveness of p53. This new information could help doctors to better identify patients with ...

Oncology & Cancer

A counterintuitive approach to fighting cancer

When you're under attack, you fight back. You gather your troops and attack the invading enemy, hoping to wound and defeat them, while supporting and treating your own injured soldiers. It's common sense.

Oncology & Cancer

Study reveals new insight into DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks ...

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