Oncology & Cancer

New studies unravel mysteries of how PARP enzymes work

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

Oncology & Cancer

A counterintuitive approach to fighting cancer

When you're under attack, you fight back. You gather your troops and attack the invading enemy, hoping to wound and defeat them, while supporting and treating your own injured soldiers. It's common sense.

Health

Study finds a new way that tobacco smoke can cause cancer

A recent study led by University of Kentucky researchers illuminates a new way that tobacco smoke may promote the development of lung cancer: inhibiting a DNA repair process called nucleotide excision repair (NER). The results ...

Genetics

Selective protection of genetic information by epigenetic system

DNA is replicated to pass genetic information to the daughter cells during cell proliferation. Replication errors, if not repaired, can lead to genetic mutations. For an individual organism, some DNA mutations may cause disease, ...

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