A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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Scientists from the Institute for Basic Science (IBS) have successfully inhibited the growth of colon tumors in mice with mismatch repair deficiency. The research team, headed by the Center's director MYUNG Kyungjae, made ...
Jun 15, 2016
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How long you live depends in part on the genes you inherit. For example, those suffering from Werner's syndrome have inherited two defective copies of a gene coding for an enzyme that is involved in DNA replication and repair.
May 2, 2016
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When it comes to replicating their DNA so they can propagate, normal cells are perfectionists. Cancer cells, on the other hand, have no problem tolerating mistakes while copying their DNA. In fact, messed-up DNA is a big ...
Apr 28, 2016
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A Telethon Kids Institute-led study has found low levels of plasma calcium, vitamin E (alpha-tocopherol) and lutein—micronutrients found in foods like spinach and eggs—to be associated with DNA damage in children.
Nov 9, 2015
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Our cells are up against a daily onslaught of damage to the DNA that encodes our genes. It takes constant effort to keep up with the DNA disrepair – and if our cells didn't bother to try to fix it, we might not survive. ...
Oct 9, 2015
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Evolutionary theory says mutations are blind and occur randomly. But in the phenomenon of adaptive mutation, cells can peek under the blindfold, increasing their mutation rate in response to stress.
Aug 25, 2015
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Cell duplication and growth is essential to sustaining life, and in order for this critical function to take place, cells must unwind the tight ball of DNA in their nucleus and then duplicate their genomic information. This ...
Jul 10, 2015
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Regardless of chronological age, people who live in neighborhoods with high crime, noise and vandalism are biologically more than a decade older than those who do not, according to a study led by researchers from the University ...
Jun 18, 2015
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A new study led by scientists at The Scripps Research Institute (TSRI) sheds light on the cause of some cancers, including breast cancer and leukemia.
May 7, 2015
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