An international team of researchers has found that some tumor cells are able to set off a caspase-activated DNAse (CAD) that promotes breaks in DNA strands after exposure to genotoxic treatments. In their paper published ...
While cancer therapies targeting specific genes or disease pathways can extend lives, they can also lead to highly resistant tumors when small reservoirs of cancer cells survive treatment, grow, and spread.
Mar 30, 2022
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Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and ...
Feb 22, 2022
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Two new studies of the developing human brain are helping researchers reconcile a long-held debate over how the brain forms. The research appears Oct. 6 in a special issue of Nature highlighting studies that contribute to ...
Oct 7, 2021
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Think about how often we sense touch or temperature. Perhaps its the warmth we feel when we hold a coffee cup, or the comfort we feel when hugging a loved one—these sensations are integral to our everyday lives and how ...
Oct 5, 2021
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Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage is to prevent the two DNA strands from separating so that the cellular machinery cannot read the instructions written ...
Jun 15, 2021
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Researchers discovered that a large amount of enterobacteria in the gut microbiota is related to long-term mortality risk in Finnish adult population.
May 11, 2021
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Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses—like influenza—that might be ...
Apr 1, 2021
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How does SARS-CoV-2 evade our immune defenses? It's a good question, actually. When SARS-CoV-2 defeats host defenses, we need to know how it does so, and conversely, when host defenses prevail, that also needs to be understood. ...
A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues. Inhibiting the function of LAT1 has been known to have anti-tumor effects, but there has been limited progress in the development ...
Jan 4, 2021
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