Scientists have made a major advance in untangling the brain circuits that lead to the powerful addictive effects of heroin, a study in the open-access journal eLife reports.
Oct 30, 2018
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When alcohol enters the brain, it causes neurons in a specialized region called the ventral tegmental area, or VTA—also known as the "pleasure center"—to release dopamine, a neurotransmitter that produces those feel-good ...
Oct 22, 2018
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Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from ...
Oct 3, 2018
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Diseases have a spectrum of risk, even those partially embedded in genes such as Parkinson's disease.
Aug 2, 2018
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A major factor underlying Parkinson's Disease (PD) pathology is the loss of dopamine neurons in the substantia nigra, and thus current therapies often aim to restore dopamine signaling. However, these treatments are not curative. ...
Jul 23, 2018
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The study of a Quebec family with an unusual gene provides novel insight into how our brain is built and, according to the McGill led team of scientists, offers a better understanding of psychiatric disorders such as depression, ...
Jun 18, 2018
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The HIV virus, which causes AIDS, has long been known to target and disable cells of the immune system, which are responsible for fighting off invading microorganisms and for suppressing malignant cancers. More recently, ...
May 23, 2018
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Standard drug treatment for Parkinson's disease can over time induce motor complications that reduce the effectiveness of restoring mobility. These complications include abnormal involuntary movements known as dyskinesias. ...
Jan 25, 2018
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Oxidative stress plays a big role in the brain cell loss that occurs in Parkinson's disease. Now scientists have their sights on a protein that inhibits one of the body's natural protections against it.
Nov 6, 2017
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The brain's own mechanisms for dealing with the loss of dopamine neurons in Parkinson's disease may be a source of the disorder's abnormal movement, according to a Northwestern Medicine study published in Neuron.
Sep 14, 2017
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