Neuroscience

Unraveling the brain's reward circuits

To some, a chocolate cake may spark a shot of pleasure typically associated with illicit drugs. A new study by Penn biologists offers some insights into that link, revealing new information about how the brain responds to ...

Parkinson's & Movement disorders

A new drug target for chemically induced Parkinson's disease

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the onset of a form of Parkinson's disease. In a new study led by scientists from the School of Veterinary Medicine, ...

Neuroscience

Study reveals roots of Parkinson's in the brain

Researchers from King's College London have uncovered the earliest signs of Parkinson's disease in the brain, many years before patients show any symptoms. The results, published in The Lancet Neurology, challenge the traditional ...

Immunology

How chronic inflammation may drive down dopamine and motivation

Growing evidence shows that the brain's dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory ...

Neuroscience

Unexplored neural circuit modulates memory strength

Learning to avoid negative experiences requires an interplay of two distinct brain circuits, one to interpret "Yikes!" and drive learning, and the other, unexpectedly, to dial in the strength of that memory, a new fruit fly ...

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