Neuroscience

Down syndrome, like Alzheimer's, is a double-prion disorder

The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. ...

Neuroscience

Blood test detects Alzheimer's in people with Down syndrome

Around 80% of people with Down syndrome develop Alzheimer's disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer's disease ...

Genetics

Scientists create novel genetic model of Down syndrome in rats

In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in Japan have genetically ...

Medical research

More effective COVID-19 treatment with immune modulatory drugs

A recent study published in the Proceedings of the National Academy of Sciences by a team of researchers at the University of Colorado Anschutz Medical Campus significantly advances the understanding of a key aspect of the ...

Medical research

Study unravels mysteries of the aging Down syndrome brain

In the first study of its kind, researchers from Sanford Burnham Prebys have uncovered molecular changes within the aging brains of individuals with Down syndrome that could help explain their cognitive challenges, including ...

Medical research

Can leukemia in children with Down syndrome be prevented?

For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down syndrome in preclinical models, paving the way to potentially prevent this cancer in the future.

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