Periodontitis is initiated by dysbiosis of the oral microbiome. Pathogenic bacteria elicit ineffective immune responses, which damage surrounding tissues and lead to chronic inflammation. Although current treatments typically ...
Aug 8, 2024
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By establishing protein design algorithms that simultaneously optimize drug candidates for both decreased immunogenic epitope content and high level stability and activity, Dartmouth's Norris Cotton Cancer Center investigator ...
Jan 28, 2015
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Variola, the virus that causes smallpox, is on the agenda of the upcoming meeting of the World Health Assembly (WHA), the governing body of the World Health Organization. The decision to be made is whether the last known ...
May 1, 2014
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A drug candidate discovered by Peter W. Schiller, Director of the Chemical Biology and Peptide Research unit at the Institut de recherches cliniques de Montréal (IRCM) and Research Professor in the Department of Pharmacology ...
Feb 18, 2016
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Since 2002, close to 300 drug candidates to treat Alzheimer's have run into clinical dead ends. But now, having learned from those failures, researchers are testing—and retesting—a batch of the most promising compounds ...
Jun 3, 2015
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A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients' TB bacteria within two ...
Jul 23, 2012
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A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences (NCATS) and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience ...
Jul 9, 2014
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NUS chemists have developed a simple and robust bio-screening method to identify anticancer drug candidates to overcome multidrug resistance (MDR).
Jul 7, 2017
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Researchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before symptoms appear. The method has now formally been classified as the international ...
Nov 2, 2015
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The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: ...
Aug 16, 2012
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