Drug discovery can be a frustrating process of trial and error. Scientists using fragment-based drug discovery link fragments of different molecules together to create a more potent drug but may not know whether a compound ...
Feb 28, 2024
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Genome-wide association studies (GWAS) on patient blood samples are useful for identifying the genetic basis of blood cell traits and their links to common diseases. While previous experiments have focused on characterizing ...
Dec 15, 2023
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Elucidating human contact networks could help predict and prevent the transmission of SARS-CoV-2 and future pandemic threats. A new study from Scripps Research scientists and collaborators points to which public health protocols ...
Dec 14, 2023
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In a novel study, researchers from the Icahn School of Medicine at Mount Sinai have introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain and loss-of-function variants across the genome.
Dec 14, 2023
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A new artificial intelligence (AI) model designed by Scripps Research scientists could help clinicians better screen patients for atrial fibrillation (or AFib)—an irregular, fast heartbeat that is associated with stroke ...
Dec 12, 2023
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Using a novel "organ-on-a-chip" model, Baker Heart & Diabetes Institute researchers have discovered a potential therapeutic target that may slow down vascular aging and reduce heart disease, kidney dysfunction and vascular ...
Dec 11, 2023
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A team of CiRA researchers, building upon their previous work on differentiating iPS cells into kidney organoids, have made significant improvements to build a better model of kidney development and diseases for use as a ...
Dec 1, 2023
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Scientists at CeMM, the Medical University of Vienna, and the University of Lausanne have succeeded for the first time in identifying and characterizing a new small molecule called "Feeblin," which can inhibit the interaction ...
Oct 24, 2023
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Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox. A new model system for studying mpox virus infections in the laboratory is providing valuable ...
Oct 16, 2023
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To discover new treatments for genetic disorders, scientists need a thorough knowledge of prior literature to determine the best gene/protein targets and the most promising drugs to test. However, biomedical literature is ...
Oct 3, 2023
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