Diseases, Conditions, Syndromes

Pfizer says tweaked COVID-19 shots boost omicron protection

Pfizer announced Saturday that tweaking its COVID-19 vaccine to better target the omicron variant is safe and works—just days before regulators debate whether to offer Americans updated booster shots this fall.

Oncology & Cancer

Molecular mechanisms reveal how to make the most of methotrexate

St. Jude Children's Research Hospital scientists have identified factors that influence how children with acute lymphoblastic leukemia (ALL) respond to methotrexate. High-dose methotrexate is a part of modern curative therapy ...

Medical research

Study examines HIV drug's potential to treat Alzheimer's

A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer's disease, and Vanderbilt University biochemist F. Peter Guengerich, Ph.D., is aiding efforts to make this approach to improving ...

Cardiology

Asthma drug potential treatment for aortic aneurysm

Aortic aneurysm – the dilation of the aorta – is a serious condition that lacks effective drug treatment. Researchers at Karolinska Institutet report in the journal PNAS, however, that a common asthma drug can retard ...

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