One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments. In some cases, tumors exhibit what is known as multidrug resistance (MDR), which significantly limits ...
Jul 22, 2022
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A combination of up to five drugs normally used to treat conditions ranging from HIV to Type 2 diabetes could destroy cancer cells, yet be less toxic than a chemotherapy drug used for recurring ovarian cancer.
Jul 14, 2022
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Imatinib, better known as Gleevec, was hailed as a "miracle" cancer drug when it entered the market in the early 2000s. Though it has been highly successful at treating early-stage chronic myeloid leukemia (CML)—a rare ...
Jun 1, 2022
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To many, tuberculosis (TB) may seem like a disease from a bygone era. But it still claims more than one million lives every year. And the problem is growing worse as Mycobacterium tuberculosis, the pathogen that causes TB, ...
May 9, 2022
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A research team led by Prof. Liu Qingsong and Liu Jing from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has recently found that nintedanib, a multikinase inhibitor of the receptor ...
Apr 7, 2022
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An antiviral drug used to treat SARS-CoV-2 remains effective against the newest variants of the evolving virus, according to Rutgers researchers.
Mar 18, 2022
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While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted ...
Mar 1, 2022
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Scientists have spotted signs of 'pre-resistance' in bacteria for the first time—signs that particular bacteria are likely to become resistant to antibiotics in the future—in a new study led by UCL and Great Ormond Street ...
Dec 15, 2021
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As the latest coronavirus variant upends expectations about the pandemic's coming months, drug manufacturers are working to expand treatment options to fight those stricken with severe disease. Even as new pills from Pfizer ...
Dec 14, 2021
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Researchers have developed a new method that uses artificial intelligence to foresee the most likely mutations of pathogens like SARS-COV-2, the virus that causes COVID-19.
Oct 25, 2021
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