Genetics

Deciphering the mutations behind drug resistance

Antimicrobial resistance in disease-causing microbes has garnered attention in recent years, but another persistent area of drug resistance is the ability for tumors to evade chemotherapy drugs. Methotrexate is one of the ...

Oncology & Cancer

Blood test picks out prostate cancer drug resistance

Scientists have developed a blood test that can identify key mutations driving resistance to a widely used prostate cancer drug, and identify in advance patients who will not respond to treatment.

Oncology & Cancer

3-D model of solid tumors explains cancer evolution

They're among the most powerful tools for shedding new light on cancer growth and evolution, but mathematical models of the disease for years have faced an either/or stand off.

Oncology & Cancer

Calculating leukemia progression

A new computational study published in the International Journal of Bioinformatics Research and Applications has shown how mutations that give rise to drug resistance occur in a form of cancer known as acute myeloid leukemia ...

Diseases, Conditions, Syndromes

New test could identify resistant tuberculosis faster

The time needed to genetically sequence the bacteria causing tuberculosis (Mtb) from patient samples has been reduced from weeks to days using a new technique developed by a UCL-led team. This could help health service providers ...

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