Cancer

New cancer strategies promising, says researcher

Dr. Tim Fenton, an expert in cancer research at the University, says the announcement of new strategies to overcome the evolution of drug resistance in tumours could dramatically increase the effectiveness of cancer therapies.

Cancer

Tracking the epigenetic evolution of a cancer, cell by cell

A powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables them to track the molecular evolution of cancers. The tools should enable a better understanding ...

Diseases, Conditions, Syndromes

Q&A: What to know about superfungus Candida auris

The multidrug-resistant fungus Candida auris has disproportionately affected New York health care facilities, raising questions about its origins, whether it's here to stay and which health care facilities have been impacted ...

Diseases, Conditions, Syndromes

Drug-resistant tuberculosis reversed in lab

About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the illness.

Cancer

Form drives function in cancer proliferation

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

Diseases, Conditions, Syndromes

Harvard undergrad's AI model helps to predict TB resistance

One of the greatest challenges in treating tuberculosis—the top infectious killer worldwide, according to the World Health Organization (WHO)—is the bacterium's ability to shapeshift rapidly and become resistant to multiple ...

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Drug resistance

Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.

Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.

Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.

This text uses material from Wikipedia, licensed under CC BY-SA