Diseases, Conditions, Syndromes

The tuberculosis health crisis in Latin American jails

High rates of tuberculosis (TB) in Latin American prisons are subverting efforts to control the disease in the wider population, and constitute a "health and human rights crisis," a study warns.

Diseases, Conditions, Syndromes

Use COVID-19 lessons to battle deadly superbugs: WHO

Lessons learned during the COVID-19 pandemic should be used to fight the spread of drug-resistant bacteria, which kill tens of thousands of people each year, the World Health Organization said Thursday.

Diseases, Conditions, Syndromes

Ending tuberculosis is a race against time and drug resistance

The tuberculosis (TB) burden in the WHO European Region as a whole is decreasing, and is down 19% overall for 2015-2019, according to the latest WHO/European Center for Disease Prevention and Control (ECDC) report Tuberculosis ...

Diseases, Conditions, Syndromes

S.Africa trial shows promise for drug-resistant TB regimen

Almost all patients who received a new treatment for highly drug-resistant tuberculosis are still clear of the disease two years after a medical trial in South Africa, findings from a long-term study showed Thursday.

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Drug resistance

Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.

Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.

Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.

This text uses material from Wikipedia, licensed under CC BY-SA