Diseases, Conditions, Syndromes

Stressed-out parasites: Overcoming drug-resistant malaria

Drug resistance to the critical antimalarial therapeutics of the artemisinin family has emerged in Southeast Asia, highlighting the need to understand how these drugs work and how they can be used more effectively. Research ...

Medical research

Researchers discover why drug for severe COPD becomes less effective

Roflumilast, a drug recently approved in the United States to treat severe chronic obstructive pulmonary disease (COPD), increases the production of a protein that causes inflammation, which possibly results in patients developing ...

Arthritis & Rheumatism

Smoking impairs treatment response in inflammatory back arthritis

Smoking impairs the response to biological drugs used to treat inflammatory arthritis affecting the lower back, known as axial spondyloarthritis, or AxSpA, for short, reveals research published online in the Annals of the ...

Medical research

Toward a cocaine vaccine to help addicts kick the habit

In their decades-long search for vaccines against drugs of abuse, scientists have hit upon a new approach to annul cocaine's addictive buzz. They report in the ACS journal Molecular Pharmaceutics that their strategy, which ...

Medical research

Study establishes zebrafish as a model for flu study

In the ongoing struggle to prevent and manage seasonal flu outbreaks, animal models of influenza infection are essential to gaining better understanding of innate immune response and screening for new drugs. A research team ...

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