Diseases, Conditions, Syndromes

Harvard undergrad's AI model helps to predict TB resistance

One of the greatest challenges in treating tuberculosis—the top infectious killer worldwide, according to the World Health Organization (WHO)—is the bacterium's ability to shapeshift rapidly and become resistant to multiple ...

Cancer

Evolution of cancer cell lines draws concern

Cell lines form the backbone of cancer research. These individual groups of cells, typically collected from patients' tumor samples and cultured to grow indefinitely in the laboratory, enable everything from basic genetic ...

Cancer

Current cancer drug discovery method flawed, study finds

The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise ...

Medications

The importance of standardizing drug screening studies

A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the ...

Diabetes

New link between obesity and diabetes found

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to ...

Neuroscience

Codeine could increase users' sensitivity to pain

Using large and frequent doses of the pain-killer codeine may actually produce heightened sensitivity to pain, without the same level of relief offered by morphine, according to new research from the University of Adelaide.

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