Medical research

From shape-shifting to therapy

(Medical Xpress)—The latest research into the intricate processes that let substances into and out of cells will help to lay the foundations for the next generation of therapies for major diseases.

Biomedical technology

Mimicking nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and muscles, and are an ...

Oncology & Cancer

Scientists discover new target for personalized cancer therapy

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...

Oncology & Cancer

Cancer avatars for personalized medicine

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have used computer simulations of cancer cells – cancer avatars – to identify drugs most likely to kill cancer cells isolated ...

Neuroscience

Mental fog with tamoxifen is real, study finds possible antidote

A team from the University of Rochester Medical Center has shown scientifically what many women report anecdotally: that the breast cancer drug tamoxifen is toxic to cells of the brain and central nervous system, producing ...

Medications

Predicting liver injury in paracetamol overdose patients

Scientists at the University of Liverpool have identified molecules in the blood that could help predict the risk of a patient developing liver injury eight hours after a paracetamol overdose.

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