Genetics

Why does making new egg cells require so much cell death?

A highly detailed study of how the roundworm C. elegans forms oocytes suggests that the egg-making process leads to the formation and subsequent destruction of cells with an extra nucleus, but that some cellular materials ...

Oncology & Cancer

A major step towards individualized cancer therapy

Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in the U.S. succeeded in establishing a powerful and convenient model to analyse human cancer.

Obstetrics & gynaecology

Preconception zinc deficiency could spell bad news for fertility

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility. Now, ...

Obstetrics & gynaecology

Like babies, eggs send signals when 'hungry'

In humans and other mammals, the female reproductive cells - the eggs or oocytes - need nourishment in order to grow and remain fertile. It is known that the egg gets its food from little arm-like feeding tubes (called filopodia) ...

Genetics

Keeping egg cells fresh with epigenetics

Keeping egg cells in stasis during childhood is a key part of female fertility. New research published today in Nature Structural and Molecular Biology sheds some light on the role of epigenetics in placing egg cells into ...

Medical research

Fertility research brings death of dogma, birth of hope

About 13 years ago, Northeastern professor Jonathan Tilly, a reproductive biologist, made a discovery that challenged everything scientists thought they knew about female reproduction. The long-held belief that mammals were ...

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