Diseases, Conditions, Syndromes

Sox9 reshapes the biliary tree in Alagille syndrome

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of this condition is abnormalities in the ducts that carry ...

Genetics

Cause of rare, fatal disorder in young children pinpointed

Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, ...

Medical research

Mechanical forces control cell fate during brain formation

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during ...

Medical research

Protein research: Supposed disorder is not disorder after all

Many, but not all, proteins in a living cell have a defined three-dimensional structure. The interrelationship between the structure and function of proteins is the focus of many research initiatives that extend to the development ...

Medical research

New mechanism of bone growth discovered

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden reports that bone growth in mice takes place in accordance with the same principles as when ...

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Embryogenesis

Embryogenesis (compound of the Greek: εμβρυο-γένεσις "embryo-genesis") is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum (or egg) which, after fertilization, is referred to as a zygote. The zygote undergoes rapid mitotic divisions with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo. It occurs in both animal and plant development, this article addresses the common features among different animals.

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