Parkinson's & Movement disorders

New findings challenge current view on origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson's disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies. It ...

Immunology

Molecular component of caffeine may play a role in gut health

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...

Neuroscience

The ever-changing brain: Shining a light on synaptic plasticity

Synapses allow neurons to communicate with one another. In the synapse, one neuron emits chemical messengers called neurotransmitters, and an adjacent neuron receives them using tiny structures called receptors. A specific ...

Cardiology

Saturated fatty acids might directly damage heart

Olive oil is universally considered a much healthier alternative to meat fat. Plant-derived oils (such as olive oil, canola oil, and vegetable oil) largely consist of unsaturated fatty acids, whereas animal fat is richer ...

Inflammatory disorders

Treatment target for diabetes, Wolfram syndrome

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children ...

Neuroscience

Neuroscientists identify mechanism for long-term memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's disease and related ...

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