Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

Genetics

Large-scale study enables new insights into rare eye disorders

Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are ...

Oncology & Cancer

Novel approach identifies highly specific anti-cancer compounds

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The compounds, called ...

Neuroscience

Novel sensors enable precise measurement of dopamine

Dopamine is an important signaling molecule for nerve cells. Its concentration could not be precisely determined with both high spatial or temporal resolution until now. A new method has now made this possible: A research ...

Diseases, Conditions, Syndromes

Improving contact-tracing apps in the COVID-19 era

An international collaboration with EPFL has developed a method to improve the performance of COVID-19 contact-tracing apps by taking into account a user's recent contacts, risk levels and shared information about tests and ...

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