Alzheimer's disease & dementia

Researchers work to block harmful behavior of key Alzheimer's enzyme

Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer's disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. ...

Medical research

Study reveals how Listeria breaches the placenta

A gut bacterium called Listeria (Listeria monocytogenes), which is often found in soft cheese, is known to present a risk to pregnant women. Listeria uses distinct tactics to breach the intestine and the placenta, using a ...

Medical research

Researchers observe protein degradation in intact brain cells

Neurodegenerative diseases like Alzheimer's, Huntington's or Parkinson's are caused by defect and aggregated proteins accumulating in brain nerve cells that are thereby paralyzed or even killed. In healthy cells this process ...

Oncology & Cancer

Exercising restraint to stall tumor growth

Many proteins undergo an assembly line-style process of glycosylation as they travel from a cellular structure called the endoplasmic reticulum (ER) to the Golgi apparatus and on through its various compartments, after which ...

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