Medical research

Researchers discover new pathway for improving metabolic health

Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...

Diseases, Conditions, Syndromes

Discovery suggests new route to fight infection, disease

New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight ...

Oncology & Cancer

The sugar-attaching enzyme that defines colon cancer

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry. The enzyme appears to drive ...

Oncology & Cancer

Researchers target undruggable cancers

A new approach to targeting key cancer-linked proteins, thought to be 'undruggable," has been discovered through an alliance between industry and academia.

Genetics

Unexpected findings uncover new understanding of gene expression

Northwestern Medicine scientists have discovered that the catalytic activity of the fly enzyme Trr and mammalian MLL3/MLL4—members of the COMPASS family of proteins central to gene expression—is not required for proper ...

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