Medical research

SIRT5 regulation of proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study published in the Dec. 3rd 2013 issue of ...

Diseases, Conditions, Syndromes

Combating the deathly Coronavirus

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate ...

Medical research

Molecule acts as umpire to make tough life-or-death calls

Researchers have demonstrated that an enzyme required for animal survival after birth functions like an umpire, making the tough calls required for a balanced response to signals that determine if cells live or die. St. Jude ...

Medical research

Researchers discover new pathway for improving metabolic health

Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...

Genetics

Chromatin marks the spot in search for disease pathways

In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of papers that characterized ...

Alzheimer's disease & dementia

A molecular scissor related to Alzheimer's disease

An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta). The study was published ...

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