An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta). The study was published ...
Oct 4, 2012
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Professor Seyun Kim's team from KAIST reported the mechanism by which cellular signaling transduction network is exquisitely controlled in mediating innate immune response such as sepsis by the enzyme IPMK (Inositol polyphosphate ...
May 4, 2017
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Researchers from IMIM, Hospital del Mar Medical Research Institute, have succeeded in determining the function of a new variant of enzyme IKKalpha (IKKα) to activate some of the genes taking part in the tumor progressions ...
Oct 4, 2012
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To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...
May 2, 2012
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Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American ...
Apr 30, 2013
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More than 35 million people around the world now live with HIV/AIDS. While drug discovery efforts to combat the disease have been successful, multiple treatments are required because the virus mutates and develops resistance ...
Dec 3, 2013
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Researchers at the University of Gothenburg, Sweden, are working to develop substances that can prevent parasites, bacteria and fungi from producing essential proteins, research that could, in the long term, lead to new drugs ...
Jun 11, 2012
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Scientists at the University Medical Center of Johannes Gutenberg University Mainz in Germany identified a novel strategy to target the oncologically relevant protein-cleaving enzyme Taspase1. Taspase1 levels are not only ...
Jul 10, 2012
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A gut bacterium called Listeria (Listeria monocytogenes), which is often found in soft cheese, is known to present a risk to pregnant women. Listeria uses distinct tactics to breach the intestine and the placenta, using a ...
Jan 26, 2015
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