Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.
Jun 9, 2022
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A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The ...
Nov 12, 2020
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Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute (IDIBELL), have identified ...
Jun 27, 2022
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Published in Nature Microbiology, a study in mice finds that the microbial basis for urinary tract infections can include localized epigenetic alterations that make additional infections more likely.
A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...
Mar 5, 2021
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Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...
Aug 4, 2021
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Cancer scientists led by principal investigator Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have combined "liquid biopsy", epigenetic alterations and machine learning to develop a blood test to detect and classify ...
Nov 14, 2018
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Research involving pediatricians from the Hospital General de Valencia has shown that the children of women who were obese or had diabetes during pregnancy developed certain epigenetic alterations that predisposed them to ...
May 12, 2023
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Researchers from Boston University School of Medicine (BUSM) have developed and tested a new computational tool, Candidate Driver Analysis (CaDrA), which will search for combinations of factors that are likely to cause a ...
Feb 19, 2019
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Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and ...
Feb 7, 2013
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