Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

Genetics

Team finds new genetic and epigenetic contributors to diabetes

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal ...

Genetics

Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off", and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

Genetics

Epigenetic profiling identifies potential COPD treatment targets

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists ...

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