Recently, Dr. Feng Lin from the College of Engineering, Peking University, published a research paper in the journal Chinese Science Life Science, revealing the regulating mechanism(s) of cancer cells with mesenchymal-like ...
Jun 15, 2022
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Mutations of the gene MLL4 in epithelial skin cells can inhibit healthy cell turnover and may lead to keratinocyte cancers, which collectively outnumber all other human cancers. Targeting pathways altered by MLL4 mutations ...
Dec 21, 2021
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A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere. However, this process does not always take place in full. Researchers at the University of Basel ...
Nov 29, 2021
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Cancer is a difficult disease to treat and to study, and can be caused by a range of genetic mutations. For instance, the mutated RAS gene causes a loss of structure in so-called epithelial tissue, a tissue type that lines ...
Nov 9, 2021
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MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells. Their new models ...
Sep 13, 2021
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With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death—it is the cancer's ability to evade ...
Apr 19, 2021
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Breast cancer is harmful enough on its own, but when cancer cells start to metastasize—or spread into the body from their original location—the disease becomes even more fatal and difficult to treat.
Mar 11, 2021
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Cancer cells can experience stress. They have to contend with attacks by the immune system or with anti-cancer therapeutics. If they attempt to colonize other tissues, they have to break away from the extracellular matrix, ...
Feb 24, 2021
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Cancer is at its most deadly when two things occur: the cancer cells metastasize, spreading to new sites in the body, and the cells become resistant to treatment. The epithelial-mesenchymal transition (EMT) is a process that ...
Dec 22, 2020
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Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, ...
Dec 16, 2020
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