Oncology & Cancer

Tissue physics plays a key role in tumor growth

Cancer is a difficult disease to treat and to study, and can be caused by a range of genetic mutations. For instance, the mutated RAS gene causes a loss of structure in so-called epithelial tissue, a tissue type that lines ...

Oncology & Cancer

Engineers grow pancreatic 'organoids' that mimic the real thing

MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells. Their new models ...

Oncology & Cancer

Research sheds new light on pancreatic cancer metastasis

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death—it is the cancer's ability to evade ...

Oncology & Cancer

New insight into how cancer spreads

Breast cancer is harmful enough on its own, but when cancer cells start to metastasize—or spread into the body from their original location—the disease becomes even more fatal and difficult to treat.

Oncology & Cancer

A gearbox for tumor cell identity changes

Cancer cells can experience stress. They have to contend with attacks by the immune system or with anti-cancer therapeutics. If they attempt to colonize other tissues, they have to break away from the extracellular matrix, ...

Oncology & Cancer

Growth factor R-spondin suppresses colorectal tumor growth

Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...

Oncology & Cancer

Researchers study how tumor cells divide in the crowd

Scientists led by Dr. Elisabeth Fischer-Friedrich, group leader at the Excellence Cluster Physics of Life (PoL) and the Biotechnology Center TU Dresden (BIOTEC) studied how cancer cells are able to divide in a crowded tumor ...

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