Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...
Sep 23, 2020
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Scientists led by Dr. Elisabeth Fischer-Friedrich, group leader at the Excellence Cluster Physics of Life (PoL) and the Biotechnology Center TU Dresden (BIOTEC) studied how cancer cells are able to divide in a crowded tumor ...
Sep 2, 2020
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A study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment. Researchers showed that a combination ...
Dec 20, 2019
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Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To undergo metastasis, cells must leave the primary tumor, invade the microenvironment, circulate ...
Nov 5, 2019
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Scientists know that the solution to preventing breast cancer won't come easily, but a collaborative team of scientists at Purdue University and the Institut National de la Santé et de la Recherche Médicale (INSERM)/Institut ...
Oct 1, 2019
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Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic. In a paper published in Cancer Research, University ...
Aug 21, 2019
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For cancer to be successful—from its point of view, anyway—the disease has to find a way to break out beyond its initial foothold and spread throughout the body. Newly published research from The University of Toledo ...
Jun 27, 2019
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A cellular identity switch protects a cancer-promoting genetic pathway from targeted therapy, researchers at The University of Texas MD Anderson Cancer Center today reported in Science Translational Medicine.
Mar 13, 2019
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The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. It can be oncogenic or tumor suppressive, depending on the cancer, but its role in colorectal cancer has not been established.
Mar 1, 2019
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As cancer cells respond to cues in their microenvironment, they can enter a highly plastic state in which they are susceptible to transdifferentiation into a different type of cell. Researchers at the University of Basel ...
Jan 14, 2019
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