Oncology & Cancer

Breast cancer cells in mice tricked into turning into fat cells

As cancer cells respond to cues in their microenvironment, they can enter a highly plastic state in which they are susceptible to transdifferentiation into a different type of cell. Researchers at the University of Basel ...

Oncology & Cancer

Scientists discover molecular key to how cancer spreads

Yale researchers have discovered how metastasis, the spread of cancer cells throughout the body, is triggered on the molecular level, and have developed a tool with the potential to detect those triggers in patients with ...

Oncology & Cancer

A gearbox for tumor cell identity changes

Cancer cells can experience stress. They have to contend with attacks by the immune system or with anti-cancer therapeutics. If they attempt to colonize other tissues, they have to break away from the extracellular matrix, ...

Oncology & Cancer

Protein loss promotes cell migration

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. It can be oncogenic or tumor suppressive, depending on the cancer, but its role in colorectal cancer has not been established.

Oncology & Cancer

Tracking the cell transitions that cause cancer

Researchers think that for cancer to develop, damaged cells have to undergo certain transitions that cause them to spread, or metastasize. Junior Tristan Bepler, a biology and computer science major, is testing this hypothesis, ...

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