Oncology & Cancer

Extra chromosomes in cancers can be good or bad

Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...

Genetics

Genes linking Alzheimer's and Down syndrome discovered

Scientists are a step closer to understanding which genes are responsible for early onset Alzheimer's disease in people with Down syndrome, thanks to a new study led by researchers at the Francis Crick Institute and UCL along ...

Genetics

Down's chromosome cause genome-wide disruption

The extra copy of Chromosome 21 that causes Down's syndrome throws a spanner into the workings of all the other chromosomes as well, said a study published Wednesday that surprised its authors.

Genetics

Research finds X doesn't always mark the spot

Research from the University of Bath has found a greater number of 'escaping genes' on the X chromosome than have been previously detected, with implications for the understanding of mental impairment in humans.

Medical research

Researchers unravel molecular roots of Down syndrome

Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain.

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