Neuroscience

Mental map of space is stabilized by sugar coated neurons

A reliable sense of space is essential for daily life and memory formation. Removing sugar coated proteins around neurons in the brains' internal gps makes the mental map of space unstable, shows a study published in the ...

Neuroscience

Neural crest cell migration in Hirschsprung disease

Ankush Gosain, MD, Ph.D., of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous ...

Medical research

Casting call: Why immobilizing helps in healing

By far, the most common injuries seen in emergency rooms in the United States are those affecting extremities. Immobilization is the most common treatment, and yet, until recently, it was unknown exactly why this technique ...

Medical research

New discovery helps researchers rethink organoid cultures

Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years. But researchers from The University ...

Neuroscience

Helping damaged nerves to re-grow

Severed nerve tracts are very difficult to treat. If at all, the damage so far can only be repaired through complex operations. At the Max Planck Institute for Polymer Research, we have developed materials that stimulate ...

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Extracellular matrix

In biology, the extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.

Extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.

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